Both about cell size control but through different mechanisms. Paper 1: feedback across phases. Paper 2: proliferation-driven variability vs mechanical relaxation. Related but not perfect structural match.
Cell size determined by control mechanisms across cell cycle phases (sizer, timer, adder strategies). Division kernel and phase-specific control govern size distribution. Population-density-dependent regulation limits total cell numbers (extrinsic feedback). Cell-size-dependent regulation suppresses size variability (intrinsic feedback). Trade-off between extrinsic and intrinsic control.
view paper→Cell proliferation generates area variability while mechanical forces regulate packing. Cell division creates size asymmetry between daughter cells. Mechanical constraints from neighbors limit expansion. Area polydispersity emerges from balance between proliferation-driven variability and mechanical relaxation. Cell-cell adhesion and cortical tension determine equilibrium distributions.
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