Both describe size homeostasis through feedback. Extrinsic noise and population structure jointly determine size distributions. Noise integration and control strategies. Same mechanism as #1 but different organisms (fibroblasts vs bacteria).
Cell size determined by control mechanisms across cell cycle phases (sizer, timer, adder strategies). Division kernel and phase-specific control govern size distribution. Population-density-dependent regulation limits total cell numbers (extrinsic feedback). Cell-size-dependent regulation suppresses size variability (intrinsic feedback). Trade-off between extrinsic and intrinsic control.
view paper→Cell size fluctuates due to noisy growth rates and size-dependent division noise. Size homeostasis mechanisms compensate for fluctuations through size control strategies. Population dynamics alter size distributions compared to single lineages - exponential population growth changes the effective size control measured in constant-volume experiments. Extrinsic growth noise and population structure jointly determine observed size distributions.
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